13q Deletion MM (CLL), Heparin Blood in Mumbai

Overview

The 13q Deletion (CLL), Heparin Blood test is a specialized genetic test performed on a heparinized peripheral blood sample to detect the deletion of chromosome 13q14, one of the most common genetic abnormalities seen in Chronic Lymphocytic Leukemia (CLL). The test is typically performed using Fluorescence In Situ Hybridization (FISH), a highly sensitive technique that identifies chromosomal abnormalities in blood cells. Detection of a 13q deletion provides valuable information about the genetic profile of CLL. When present as the sole cytogenetic abnormality, it is generally associated with a more favorable prognosis compared to other chromosomal abnormalities. The test assists healthcare providers in disease classification, prognostic assessment, treatment planning, and patient monitoring. It is often performed alongside other CLL prognostic markers such as 11q (ATM) Deletion, 17p (TP53) Deletion, Trisomy 12, and IGHV Mutation Analysis for a comprehensive evaluation.

Why Take This Test?

• To detect 13q deletion associated with Chronic Lymphocytic Leukemia (CLL). To assist in the diagnosis and classification of CLL. To evaluate disease prognosis and genetic risk. To support personalized treatment planning. To complement other cytogenetic and molecular tests. To monitor disease progression and response to therapy.

What It Measures

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